Preclinical Stage — Building the Future of Drug Discovery

Drug discovery, redefined by computation.

Axia Discovery combines physics-based molecular simulation, generative AI, and multi-omics data to identify and validate novel drug candidates — faster, and with greater precision than conventional approaches.

10×
Faster hit identification
1B+
Compounds screened virtually
92%
Binding affinity accuracy
The Axia Platform

End-to-end computational drug discovery

From target to candidate, our integrated platform compresses timelines while elevating the quality of every decision.

Target Identification

Genomics · Proteomics

Multi-omics integration and network biology to uncover disease-relevant targets with high therapeutic confidence.

Virtual Screening

Docking · ADMET

Ultra-large library docking against validated targets — screening billions of compounds in days with ML-ranked hit selection.

Generative Chemistry

GenAI · De Novo Design

Graph neural networks and diffusion models generate novel scaffolds optimized for selectivity, potency, and synthetic accessibility.

Molecular Dynamics

GROMACS · OpenMM

GPU-accelerated MD simulations reveal binding mechanisms and conformational dynamics invisible to static docking.

ADMET Prediction

PK/PD · Safety

Deep learning ADMET models trained on 2M+ experimental data points predict pharmacokinetic liabilities early in the campaign.

Lead Optimization

Active Learning · FEP

Bayesian optimization loops integrate experimental feedback in real time, guiding medicinal chemistry toward the ideal candidate.

In Silico Pipeline

Computationally-driven discovery programs

Partnership inquiries →
Target ID
Virtual Screen
Hit-to-Lead
Lead Opt.
Preclinical
AXD-001LEAD
Oncology — Solid Tumors
Undisclosed peptide target
Hit-to-Lead
AXD-002
Neurodegeneration
Amyloidogenic peptide modulator
Virtual Screening
AXD-003
Inflammatory Disease
Undisclosed peptide target
Target Validation

All programs are in silico / preclinical stage · Pipeline subject to change as programs advance

Scientific Foundation

Rigorous methodology, measurable outcomes

Our platform combines state-of-the-art computational methods with validated workflows to deliver reliable predictions.

10×
Faster hit identification
Compared to traditional HTS
1B+
Compounds screened virtually
Per discovery campaign
92%
Binding affinity accuracy
Validated against experimental data
FEP+
Physics-based methods
Free energy perturbation & MD

Publications

Publications coming soon.
Our team is preparing peer-reviewed manuscripts on our computational methodologies.
Our Team

Science-driven leadership

Axia Discovery was founded on the belief that computation is the most powerful tool in modern drug discovery.

VZ
Dr. Valentin Zhigulin
Founder

Computational scientist and entrepreneur building next-generation in silico drug discovery platforms. Combining physics-based molecular simulation with machine learning to accelerate the path from target to therapeutic.

We're growing. Axia Discovery is actively building a world-class team in computational chemistry, machine learning, and drug discovery. Interested in joining? Get in touch
Partner with Axia

Ready to accelerate your drug discovery program?

Whether you're seeking a computational co-development partner, licensing opportunities, or looking to advance a difficult target — let's talk.

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